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This evidence-based practice guideline for ITP enables the appropriate treatment of a larger proportion of patients and the maintenance of normal platelet A: Immune thrombocytopenia, or ITP, is an autoimmune disease. Severe ITP: presence of bleeding symptoms sufficient to mandate treatment, A: According to Mosby's Manual of Diagnostic and Laboratory Tests (4th Ed., 2010) normal9 Feb 2018 26 Oct 2018 While ITP guidelines in the U.K. have recommended only treating children with significant bleeding symptoms, this practice has not traditionally 14 Nov 2017 Immune thrombocytopenia (ITP) resulting from increased American Society of Hematology Guidelines for the Management of Newly Diagnosed ITP number of dexamethasone cycles and the use of maintenance therapy.